KRAS is one of the most frequently mutated oncogenes in human cancers and plays a central role in regulating signaling pathways that control cell proliferation, survival and metabolism. Recent ...

Cells rely on complex signaling networks in which different molecular pathways communicate with one another. Small GTPases ...

Uncover the latest and most impactful research in Hippo Signaling Pathway in Cancer Biology. Explore pioneering discoveries, insightful ideas and new methods from leading researchers in the field.

Our understanding of how cells interact with each other has been driven for decades by the central concept of ...

Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

Acute myeloid leukemia has long been considered a disease that shrugs off glucocorticoids. While these steroid hormones form ...

Researchers reviewed evidence linking GLP-1 and GLP-1 receptor agonists to chronic pain modulation through gut microbial, ...

An international research team led by Dr. Lucia Torres Fernández from the working groups of Professor Dr. Julie George and Professor Dr. Roman Thomas at the University of Cologne has identified a ...

Idiopathic pulmonary fibrosis (IPF) is a chronic disease in which healthy lung tissue is gradually replaced by scar tissue. While the early events that initiate this change are poorly understood, ...

Our understanding of how cells interact with each other has been driven for decades by the central concept of receptor-mediated signal transduction.

Gastric cancer remains one of the world’s deadliest malignancies, ranking fifth among the most commonly diagnosed cancers and ...

A new study has uncovered a previously unrecognized function of the mitochondrial antiviral signaling protein (MAVS) under hypoxic conditions, revealing that MAVS can respond not only to viral ...